GHK-Cu vs retinol: two routes to collagen synthesis research
Retinoids and the copper tripeptide GHK-Cu are both studied for collagen synthesis, but they reach it through very different upstream mechanisms.
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The language of life, one sequence at a time
Peptide research notes from Senna Research: mechanisms, published studies, analytical testing and handling, for laboratory research use only.
GHK-Cu and collagen research notes: copper, zinc and vitamin C
GHK-Cu is one of the few peptides in its niche with human trial data. Notes on that evidence and on the copper, zinc and vitamin C biochemistry around collagen.
Read article →Peptide handling, purity and stability in laboratory research
A protocol is only as reliable as the material and handling behind it. Label claims, aseptic technique and product-specific storage each need attention.
Read article →GLP-1 body composition research: lean mass in the trial data
Weight lost in GLP-1 trials is not all fat. DXA data, the STEP 1 trial and the BELIEVE combination study show lean mass is a measurable part of the picture.
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MOTS-c research: a mitochondrial peptide that declines with age
MOTS-c is encoded by mitochondrial DNA, falls in circulation with age, and rises after aerobic exercise. Most functional evidence still comes from aged mice.
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Semax research: BDNF, neuroplasticity and neuroprotection models
Semax is studied less as a focus peptide than as a probe of neuroplasticity, cognition signaling and neuronal resilience in experimental models.
Read article →Peptide certificate of analysis: three checks that make it real
A federal case over forged lab certificates shows how much weight a certificate of analysis carries. Three checks separate a real lab report from a marketing PDF.
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FDA peptide reclassification: what it would and would not change
The FDA is reviewing whether BPC-157, TB-500 and other peptides leave the compounding-restricted category. It would open one channel and leave the rest unchanged.
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BPC-157 gastric stability and three decades of preclinical research
Most peptides degrade quickly in stomach acid. BPC-157, a fragment of a protective gastric protein, does not, and that stability is where its research story starts.
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MOTS-c research: a mitochondrial peptide in metabolic aging
MOTS-c is encoded in mitochondrial DNA, not nuclear DNA. Preclinical work links it to AMPK-like glucose signaling and to metabolic aging.
Read article →GHK-Cu gene expression: why direction matters more than 4,000 genes
The number of genes GHK-Cu modulates is widely quoted. The more informative result is which way those genes move, and how coherently they cluster.
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Thymosin beta-4 and TB-500: the actin-binding repair pathway
Thymosin beta-4 is a 43-amino-acid protein found in nearly every cell. TB-500 corresponds to its actin-binding fragment, and most of the evidence is still preclinical.
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