5-AMINO-1MQ

5-AMINO-1MQ is a small-molecule compound studied for its interaction with nicotinamide N-methyltransferase (NNMT). It is commonly referenced in metabolic regulation research, including enzymatic and cellular pathway investigations.

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Controlled handling

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Specifications

Product & molecular data

Lot & handling

SKU: SR-2160
Category: Metabolic Research
Storage: -20 °C, sealed, protected from light
Availability: In stock

Molecular

Sequence: Not available
Molecular formula: Not available
Molecular weight: Not available
CAS number: N/A
Storage conditions: −20 °C sealed and desiccated, protected from light
Format: Lyophilized Vial

Analytics

Testing & quality

When a lot certificate is on file we report identity, purity, and appearance. We publish analytical data only — never dosing information or outcome claims.

RP-HPLC

Chromatographic purity against a qualified reference standard.

LC-MS / ESI-MS

Identity by observed versus theoretical molecular mass.

Karl Fischer / Loss on Drying

Residual moisture in lyophilized material.

Endotoxin & Bioburden

Contaminant screening on raw material and finished lots.

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Research background

Published research context

Summary of the published literature this reference material is used in.

Telomere Biology

Investigated in cell-culture models of telomere maintenance and replicative ageing.

Gene Expression

Studied for reported effects on transcriptional regulation in experimental systems.

Senescence Models

Referenced in literature examining cellular senescence markers in vitro.

NNMT Interaction Studies

5-AMINO-1MQ is primarily examined for its inhibitory interaction with NNMT, an enzyme involved in nicotinamide methylation and NAD-related metabolism [1,2]. By modulating NNMT activity in experimental systems, researchers evaluate downstream shifts in methyl donor utilization, enzymatic output, and pathway-level signaling. This compound is often used as a tool molecule in studies focused on mechanistic mapping rather than outcome-driven claims.

Metabolic Pathway Exploration

NNMT has been linked in research literature to metabolic adaptation, lipid handling, and mitochondrial signaling in controlled models [2]. As a result, 5-AMINO-1MQ is frequently included in enzyme kinetics assays, pathway modulation studies, and comparative screening panels. Its defined structure supports reproducible experimental setups across biochemical assays and cell-based research models.

Molecular Characterization and Assay Use

Because pathway studies depend on consistency, researchers commonly pair 5-AMINO-1MQ with analytics that quantify enzyme activity, transcript shifts, or metabolite changes [1]. These workflows help clarify NNMT-associated biochemical relationships and support hypothesis testing for metabolic network behavior.

Key Specs