01
Telomere Biology
Investigated in cell-culture models of telomere maintenance and replicative ageing.
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Endocrine Research
In stockPT-141
PT-141 is a synthetic peptide studied for its interaction with central melanocortin receptors and neuroendocrine signaling pathways [1,2] .
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- Controlled handling
Specifications
Product & molecular data
Lot & handling
- SKU
- SR-2297
- Category
- Endocrine Research
- Storage
- -20 °C, sealed, protected from light
- Availability
- In stock
Molecular
- Sequence
- Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH
- Molecular formula
- C50H68N14O10
- Molecular weight
- 1025.16 g/mol
- CAS number
- 189691-06-3
- Storage conditions
- −20 °C sealed and desiccated, protected from light
- Format
- Lyophilized Vial
Analytics
Testing & quality
When a lot certificate is on file we report identity, purity, and appearance. We publish analytical data only — never dosing information or outcome claims.
01
RP-HPLC
Chromatographic purity against a qualified reference standard.
02
LC-MS / ESI-MS
Identity by observed versus theoretical molecular mass.
03
Karl Fischer / Loss on Drying
Residual moisture in lyophilized material.
04
Endotoxin & Bioburden
Contaminant screening on raw material and finished lots.
Research background
Published research context
Summary of the published literature this reference material is used in.
02
Gene Expression
Studied for reported effects on transcriptional regulation in experimental systems.
03
Senescence Models
Referenced in literature examining cellular senescence markers in vitro.
Central Melanocortin Signaling
PT-141 interacts primarily with MC3R and MC4R, enabling research into central melanocortin signaling mechanisms [1].
Neuroendocrine Pathways
Studies examine PT-141 in relation to neurotransmitter modulation and hypothalamic signaling networks [2].
Peptide Design
PT-141 is structurally related to melanotan peptides but modified for receptor selectivity and signaling behavior [1].
Key Specs
- Peptide class: melanocortin agonist
- Research context: neuroendocrine signaling
- References: PubChem, PubMed [1,2]
Referenced Citations
- PubChem, PT-141: https://pubchem.ncbi.nlm.nih.gov/compound/PT-141
- PubMed, Melanocortin receptor agonists: https://pubmed.ncbi.nlm.nih.gov/12621038/
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